Acidic pH interferes with Candida persistence
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چکیده
منابع مشابه
Regulation of antigen presentation by acidic pH
The effect of pH on functional association of peptide antigens with APC membranes was investigated by using aldehyde-fixed B cells and class II-restricted T cell hybridomas to assess antigen/MHC complex formation. The results indicated that the rate and extent of functional peptide binding was markedly increased at pH 5.0 as compared with pH 7.3. The pH dependence of binding was preserved after...
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bounded) organelles are involved in the dynamic membrane trafficking processes essential for protein sorting and targeting, receptor-mediated endocytosis, neural or hormonal signal transduction and other processes (Mellman et al., 1986; Goldstein et al., 1985). These organelles include the Golgi apparatus, secretory vesicles, coated vesicles, endosomes, lysosomes and synaptic vesicles. Their lu...
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ژورنال
عنوان ژورنال: Nature Reviews Microbiology
سال: 2017
ISSN: 1740-1526,1740-1534
DOI: 10.1038/nrmicro.2017.72